Bio-X4 Reviews – Does Bio X4 Work For Weight Loss?

Bio-X4 is an organic probiotic supplement with 12 billion CFUs from 5 powerful strains which improves overall digestion and promotes weight loss.
Colon Health Magazine is supported by our readers. When you buy something through a link on this page, we may earn an affiliate commission. See our Advertiser Disclosure.

What is Bio-X4?

Customers looking for a pure organic probiotic brand with weight loss benefits should strongly consider trying Nucific Bio X4, a natural digestive health supplement containing some of the most potent existing strains.

This formula comes highly recommended by top RDNs worldwide for its benefits in improving gut health, its nutritional value, and its weight management properties.

Bio-X4 also boosts energy levels and supports the immune system.

Features and Rating

Editor’s Rating

Bio X4

Powerful Weight Loss and Digestive Health Supplement


Bio X4 is an organic probiotic supplement with 12 billion CFUs from 5 powerful strains which improves overall digestion and promotes weight loss.


*All individuals are unique. Your results can and will vary.

  • 1 Bottle: $49.00
  • 3 Bottle: $129.00
  • 6 Bottle: $240.00

Buy Now

  • Ingredients
    4.9/ 5


  • Value For Cost
    4.7/ 5

    Value For Cost

  • Manufacturer
    4.9/ 5


  • Safety
    4.8/ 5


Quick Facts and Specs

Bio X4 is an organic probiotic supplement with 12 billion CFUs from 5 powerful strains which improves overall digestion and promotes weight loss.

  • Form:Capsules
  • Brand:Nucific by Pacific Health Supplements LLC
  • Contact:Pacific Health Supplements LLC,8391 Beverly Blvd., Ste. 471; Los Angeles; 90048; United States
    Phone: 888-679-5520
  • Ingredients:Lactobacillus Acidophilus, Lactobacillus Rhamnoses, Lactobacillus Plantarum, Bifidobacterium Lactis, Bifidobacterium Animalis, Green Tea, Bromelain, Lipase, Amylase, Caralluma Fimbriata
  • Cost:$49
  • Uses:Digestive Health and Weight Loss
  • Type:Probiotic Weight Loss Supplement

Pros and Cons of BioX4


  • Bio X4 by Nucific can optimize digestion.
  • This supplement can curb appetite and cravings.
  • It stimulates fat burning and can promote weight loss.
  • Bio X4 pills can enhance your energy levels.
  • The product can strengthen the immune system.


  • The results may vary for individual customers.
  • The dosage is 3 capsules per day.
  • High demand may lead to low stock at times.

About the Brand

The manufacturer of Bio X4 and the entire Nucific brand is a well known and highly regarded health and wellness supplement company in Los Angeles, California called Pacific Health Supplements, LLC. The organization formed in 2014.

The Chief Medical Officer of Nucific is Dr Amy Lee, a physician certified by the American Board of Internal Medicine. She ensures that all Bio X4 products are 100% backed by science and research, safe, all-natural, and effective.

How Does Bio X4 Work?

The Bio X4 formula is rich is 5 potent probiotic strains. These are healthy bacteria which live in the intestines, eliminating harmful microbes and forming an optimal gut microbiome.


*All individuals are unique. Your results can and will vary.

An article in the American Journal of Clinical Nutrition discussed the beneficial role of probiotics in determining survival and growth in the digestive system [1].

The supplement also includes key enzymes which break down sugars, carbs, proteins, and other foods for smoother digestion. On the whole, this promotes healthy, regular bowel movements and eases symptoms like diarrhea, constipation, gas, and bloating.

The formula also has fiber, which helps push the food along the digestive tract. In addition, it fills the gut to suppress appetite, so you take in fewer daily calories.

A study on human participants in Nutrients concluded that additional fiber intake promoted a feeling of fullness and improved general wellbeing [2].

Bio X4 includes some caffeine and other bioactive compounds which could speed up the metabolism, causing the body to enter a state of thermogenesis. This leads to rapid fat burning and weight loss.

A general population sample study published by the European Journal of Clinical Nutrition concluded that there was an association between high caffeine intake and successful weight management [3].

The supplement has anti-inflammatory properties which can decrease swelling in the body, including the gut, and also enhance heart and joint health.

Nucific Bio-X4 is high in antioxidants, which abolish damaging free radicals in your system. This leads to a decline in oxidative stress, strengthening the immune system and promoting bodily repair.


*All individuals are unique. Your results can and will vary.

What are the Ingredients in Bio X4?

bio x4
biox4 supplements – Facts

These are some of the primary active Bio X4 ingredients:


This is a proteolytic enzyme derived from the pineapple fruit. It improves digestion by helping to break down food, for improved bowel movement regularity and a decrease in issues like diarrhea and gas.

Rich in anti-inflammatory properties, it reduces swelling in the gut. It also helps lessen pain and swelling in joints and it supports the health of the heart and other organs. Bromelain has potent antioxidants which strengthen the immune system.


A pharmacological overview in Life discussed the benefits of bromelain as a bioactive compound, including its positive effects on digestion, respiration, circulation, and immune functioning [5].

Caralluma Fimbriata

This is a cactus-like plant which grows in India, and it’s high in fiber which promotes improved digestion. The fiber also suppresses appetite and cravings, helping you to lose weight by decreasing your calorie intake.

A study on overweight adults published in Scientific Reports concluded that Caralluma Fimbriata intake over 16 weeks led to weight and fat loss as well as a decrease in waist circumference [6].

Green Tea

Derived form the leaves of the Camellia Sinensis plant, green tea has bioactive compounds called catechins (like EGCG) which offer health, immunity, and weight loss benefits.

Green tea has caffeine, which speeds up the metabolism. This promotes fat burning and weight loss, improves exercise performance, provides energy, and staves off fatigue.


A review of the research published by the American Journal of Clinical Nutrition found support for the role of green tea in increasing metabolism, curbing appetite, and promoting fat and weight loss [7].


What Do the Reviews Say?

The vast majority of the Bio X 4 reviews had glowing comments about this product and the great health, digestion, and weight loss benefits it provides.

Most said it was more than worth the cost and had few if any Bio X4 complaints. Here are a selection of some of the best user comments:

It Worked For Me

I started taking it with my meals and it curbed my appetite so that I avoided overeating. My “salt-&-crunchy” cravings went away. With minimal effort, my weight is going down. Once I reach a plateau, I will start adding in exercise. Pleased with my results. No noticeable side effects… ~ M. Wolford

I Like Them So Far

I really noticed a difference in my appetite control. One day accidentally forgot to take it and could tell! I just wish they were in stock! ~ Lauren Huite

It Works

I was very skeptical. It has changed my life. I’ve been taking them for 3 weeks. I am going to order monthly now. ~ Holly L.

Rating for Claimed Benefits

Here is our ratings, based on scientific evidence, of how likely Bio X4 will be effective for its claimed benefits:

  • Enhances Digestive Health*5.0/5
  • Boosts Energy Levels*4.8/5
  • Promotes Weight Loss*5/5
  • Strengthens the Immune System*4.9/5

Note: We used the insights from our research and analysis to assign a star rating from one to five (five being the best; one being the worst) to this product.

In Summary – Bio X4 Review

Bio-X4 is an organic probiotic supplement which enhances your digestive system, boosts energy levels, suppresses hunger and cravings, and speeds up the metabolism for fat burning and weight loss. It’s a healthy, antioxidant-rich formula which also supports general health and immunity.

Most of the reviews for Bio X4 were from users who loved the supplement and were now taking it regularly. Many said they subscribed, because the boost in digestion and consistent weight loss made it more than worth it.

This supplement is doctor formulated, and contains 100% organically sourced ingredients. It’s free of gluten, common allergens, and synthetic or chemical additives.

There have been no reported side effects from users. Highly recommended by leading RDNs, Bio-X4 is one of the very best probiotic weight loss brands on the market.

Frequently Asked Questions

Q.How to Take Bio X4?

A. The manufacturer recommends that you take 1 capsule with each meal, for 3 total. The maximum dosage is 6 capsules per day, or 3 with each meal. Do not consume more than this amount in a 24-hour period under any circumstances.

Q. Is Nucific Bio X4 Safe?

A. BioX4 is a supplement which includes only pure organically sourced ingredients, with no harmful chemical additives or fillers, gluten, or common allergens. There should be no BioX4 side effects. They manufacture all products in a GMP certified facility in the USA.

Q.What is the Nucific Bio X 4 Return Policy?

A.The manufacturer has an unconditional 90-day money back guarantee on all products. If you are not happy with Bio X4, contact customer service for instructions. Then send the order back within 90 days of the purchase. You’ll get a full, hassle-free refund.

Q.Where to Buy Bio-X4?

A. The best place to buy this supplement is on the official website, so you can benefit from their great deals, promos, and stellar customer service. However, Nucific Bio X4 is also for sale from other retailers like Amazon and Walmart.

On the official site, you save money if you buy in bulk, and you can joint the Nucific New You Club for additional discounts. The price list is as follows:

  • 1 Bottle – $49
  • 3 Bottles – $129
  • 6 Bottles – $240

Q.Does BioX4 Work?

A.Yes, Bio-X4 is a potent natural formula with ingredients that all have significant scientific support for their efficacy in weight loss and digestive health. In addition, the majority of the Bio X4 reviews Nucific reported powerful results.

Q.What Sets It Apart From the Competition?

A.The Nucific brand has an excellent reputation in the market for producing powerful, safe, effective organic health supplements. Bio-X4 is doctor developed and approved by Physician Dr. Amy Lee, who is board certified and specializes in nutrition and obesity.

Where To Find It?


Read All Bio X4 Customer Reviews

Bio-X4 Reviews – Does Bio X4 Work For Weight Loss?
Review this Product
Write a Review
Review Guidelines

Your email address will not be published.

Your Rating:05

Thanks for submitting your comment!

12 Sources

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy. Colon Health Magazine adheres to strict editorial integrity standards. To the best of our knowledge, all content is accurate as of the date posted, though offers contained herein may no longer be available. The opinions expressed are the author's alone and have not been provided, approved or otherwise endorsed by our advertisers.

*Individual Results may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. Your health and wellness is unique to you, and the products and services we review may not be right for your circumstances. The information contained in this website is provided for educational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. For personal advice, please consult with a medical professional.

Disclosure of Material Connection: Some of the links in the post above are "associate sales links." This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsements and Testimonials."

Related Products